Publications

* denotes corresponding author

Journal articles

    2025
  1. Spatiotemporal distribution of YAP and importin-β in nucleus and cytosol after wounding of adjacent cells.
    Boyuan Xiao, Saori Sasaki, Naoki Takeishi, Toshihiro Sera, Susumu Kudo*.
    In Vitro Cell. Dev. Biol.-Anim. 2025, Accepted.
  2. Phase changes of the flow rate in the vertebral artery caused by debranching thoracic endovascular aortic repair: effects of flow path and local vessel stiffness on vertebral arterial pulsation.
    Naoki Takeishi*, Li Jialong, Naoto Yokoyama, Takasumi Goto, Hisashi Tanaka, Shigeru Miyagawa, Shigeo Wada.
    Med. Eng. Phys. 2025, 140:104348.
  3. Inertial focusing of spherical capsule in pulsatile channel flows.
    Naoki Takeishi*, Kenta Ishimoto, Naoto Yokoyama, Marco Edoardo Rosti.
    J. Fluid Mech. 2025, 1008:A46
    Simulating the fluid dynamics of moving cells to map its location (EurekAlert)
     Press release
  4. Spatiotemporal distribution of PKCα, PIP3, Moesin, Cdc42, MARCKS, Scriblle, and Arf6 before directed cell migration in monolayers.
    Quanzhi Lu, Katsuyuki Ushijima, Saori Sasaki, Toshihiro Sera, Naoki Takeishi, Susumu Kudo*.
    Biochem. Biophys. Res. Commun. 2025, 750:151371.
    5. 2024
  5. Microscale topographies on biomaterial surfaces modulate cell migration.
    Saori Sasaki*, Keita Eguchi, Ming We, Ryu Takahashi, Toshihiro Sera, Naoki Takeishi, Susumu Kudo.
    J. Biorheol. 2024, 38:120-125.
  6. Quantification of membrane protein diffusion on endothelial cell surfaces under shear stress using a photochromic fluorescent protein.
    Naoto Kawasaki, Keita Hamasaki, Saori Sasaki, Naoki Takeishi*, Susumu Kudo*.
    J. Biorheol. 2024, 38:88-93.
  7. Numerical-experimental estimation of the deformability of human red blood cells from rheometrical data.
    Naoki Takeishi*, Tomohiro Nishiyama, Kodai Nagaishi, Takeshi Nashima, Sugihara-Seki.
    J. Rheol. 2024, 68:837-848.
    Featured article (Journal's Best).
    Scilight (Science Highlight)
    Press release
  8. Construction of multilayered small intestine-like tissue by reproducing interstitial flow.
    Sayaka Deguchi*, Kaori Kosugi, Naoki Takeishi, Yukio Watanabe, Shiho Morimoto, Ryosuke Negoro, Fuki Yokoi, Hiroki Futatsusako, May Nakajima-Koyama, Mio Iwasaki, Takuya Yamamoto, Yoshiya Kawaguchi, Yu-suke Torisawa, Kazuo Takayama*.
    Cell Stem Cell. 2024, 31:1-12.
    Press release
  9. Numerical analysis of viscoelasticity of two-dimensional fluid membranes under oscillatory loadings.
    Naoki Takeishi*, Masaya Santo, Naoto Yokoyama, Shigeo Wada.
    Results Eng. 2024, 22:102304.
  10. Viscoelasticity of suspension of red blood cells under oscillatory shear flow.
    Naoki Takeishi*, Marco Edoardo Rosti, Naoto Yokoyama, Luca Brandt.
    Phys. Fluids. 2024, 36:041905.
  11. Spatiotemporal distribution of PTEN before directed cell migration in monolayers.
    Quanzhi Lu, Saori Sasaki, Toshihiro Sera, Susumu Kudo*.
    In Vitro Cell. Dev. Biol.-Anim. 2024, 60:1160-1173.
  12. Overstretching alveolar epithelial type II cells decreases surfactant secretion via actin polymerization and intracellular trafficking alteration.
    Shigesato Inoue*, Junpei Nagao, Kouhei Kawamoto, Keiko Kan-o, Satoru Fukuyama, Saori Sasaki, Susumu Kudo, Isamu Okamoto, Toshihiro Sera.
    Heliyon. 2024, 10:e33499.
    13. 2023
  13. The effect of stiff substrates on the collective migration of A549 cells.
    Saori Sasaki, Zhaoyi Du, Ryu Takahashi, Qi Sun, Toshihiro Sera, Susumu Kudo*.
    J. Biomech. Sci. Eng. 2023, 18:23-00298.
  14. Effect of O2 concentration on arteriole diameter near stimulated neurons in the cortex.
    Tatsuya Sato, Saori Sasaki, Toshihiro Sera, Susumu Kudo.
    J. Biorheol. 2023, 37:9-12.
  15. Cold-induced vasodilation response in a Japanese cohort: insights from cold-water immersion and genome-wide association studies.
    Yoshiki Yasukochi*, Toshihiro Sera, Taiki Kohno, Yusuke Nakashima, Musashi Uesugi, Susumu Kudo.
    J. Physiol. Anthropol. 2023, 42:2.
    16. 2022
  16. A maternal high-fat diet induces fetal origins of NASH-HCC in mice.
    Takao Takiyama, Toshihiro Sera, Masanori Nakamura, Masato Hoshino, Kentaro Uesugi, Shin‐ichi Horike, Makiko Meguro‐Horike, Ryoichi Bessho, Yuri Takiyama, Hiroya Kitsunai, Yasutaka Takeda, Kazuki Sawamoto, Naoto Yagi, Yuji Nishikawa, Yumi Takiyama*.
    Sci. Rep. 2022, 12:13136.
  17. Influence of the difference in refractive index on the interface of an object and the surroundings in near-infrared fluorescence tomography.
    Maho Takematsu, Masakazu Umezawa*, Toshihiro Sera, Yuichi Kitagawa, Hiroyuki Kurahashi, Shuta Yamada, Kyohei Okubo, Masao Kamimura, Hideo Yokota, Kohei Soga.
    App. Opt. 2022, 61:638-644.
    18. 2021
  18. Spatiotemporal distribution of PKCα, Cdc42, and Rac1 before directed cell migration.
    Saori Sasaki, Ryu Takahashi, Yangfeng Luo, Kengo Chujo, Toshihiro Sera, Susumu Kudo*
    Biochem. Biophys. Res. Commun. 2021, 584:26-31.
  19. Visualizing the flow patterns in an expanding and contracting pulmonary alveolated duct based on microcomputed tomography images.
    Toshihiro Sera*, Naoki Kamiya, Taichi Fukushima, Gaku Tanaka*.
    J. Biomech. Eng. 2021, 143:074501.
    20. 2020
  20. Voxel-based simulation of flow and temperature in the human nasal cavity.
    Shinya Kimura, Takashi Sakamoto, Toshihiro Sera, Hideo Yokota, Kenji Ono, Denis J. Doorly, Robert C. Schroter, Gaku Tanaka*.
    Comput. Methods Biomech. Biomed. Engin. 2020, 24:459-466.
  21. Low-frequency oscillations of finger skin blood flow during the initial stage of cold-induced vasodilation at different air temperatures.
    Toshihiro Sera*, Taiki Kohno, Yusuke Nakashima, Musashi Uesugi, Susumu Kudo.
    J. Physiol. Anthropol. 2020, 39:37.
  22. A metabolic reaction-diffusion model for PKCα translocation via PIP2 hydrolysis in an endothelial cell.
    Toshihiro Sera*, Shiro Higa, Yan Zeshu, Kyosuke Takahi, Satoshi Miyamoto, Tetsuya Fujiwara, Hideo Yokota, Saori Sasaki, Susumu Kudo.
    Biochem. J. 2020, 477:4071-4084.
  23. Heterogeneous reorganization of actin filaments in living endothelial cells in response to shear stress.
    Toshihiro Sera*, Marie Terada, Susumu Kudo.
    J. Biorheol. 2020, 34:18-24.
  24. Mathematical models for intra- and inter-cellular Ca2+ wave propagations.
    Toshihiro Sera*, Susumu Kudo.
    J. Biorheol. 2020, 34:9-17.
  25. Computed Tomography for In Vivo Deep Over-1000 nm Near-Infrared Fluorescence Imaging.
    Masakazu Umezawa*, Toshihiro Sera, Hideo Yokota, Maho Takematsu, Masahiko Morita, Gil Yeroslavsky, Masao Kamimura, Kohei Soga*.
    J. Biophotonics. 2020, 13:e202000071.
    26. 2019
  26. The effectiveness of an averaged airway model in predicting the airflow and particle transport through the airway.
    Toshihiro Sera*, Hiroaki Kuninaga, Kazuaki Fukasaku, Hideo Yokota, Masao Tanaka.
    J. Aerosol. Med. Pulm. Drug. Deliv.. 2019, 32:278-292.
  27. Heterogeneous structure and surface tension effects on mechanical response in pulmonary acinus: A finite element analysis.
    Kenichiro Koshiyama*, Keisuke Nishimoto, Satoshi Ii, Toshihiro Sera, Shigeo Wada.
    Clin. Biomech. 2019, 66:32-39.
  28. Voxel-based modeling of airflow in the human nasal cavity.
    Shinya Kimura*, Takashi Sakamoto, Toshihiro Sera, Hideo Yokota, Kenji Ono, Denis J. Doorly, Robert C. Schroter, Gaku Tanaka.
    Comput. Methods Biomech. Biomed. Engin. 2019, 22:331-339.
  29. The disuse effect on canal network structure and oxygen supply in the cortical bones of rats.
    Toshihiro Sera*, Hiroaki Kobayashi, Masato Hoshino, Kentaro Uesugi, Takeshi Matsumoto, Masao Tanaka.
    Biomech. Model. Mechanobiol. 2019, 18:375-385.
  30. Unloading of intercellular tension induces the directional translocation of PKCα.
    Toshihiro Sera, Masataka Arai, Zhunghua Cui, Koichi Onose, Alireza Karimi, Susumu Kudo.
    J. Cell. Physiol. 2019, 234:9764-9777.
  31. A combination of the finite element analysis and experimental indentation via the cornea.
    Alireza Karimi*, Reza Razaghi, Toshihiro Sera, and Susumu Kudo.
    J. Mech. Behav. Biomed. Mater. 2019, 90:146-154.
    32. 2018
  32. Three-dimensional model of intracellular and intercellular Ca2+ waves propagation in endothelial cells.
    Toshihiro Sera*, Shingo Komine, Masataka Arai, Yasuhiro Sunaga, Hideo Yokota, Susumu Kudo.
    Biochem. Biophys. Res. Commun.. 2018, 505:781-786.
  33. Impact of Diabetes and an SGLT2 Inhibitor on Glomerular Number and Volume in db/db Mice as Estimated by Synchrotron Radiation Micro-CT at SPring-8.
    Yumi Takiyama*, Toshihiro Sera, Masanori Nakamaura, Kanaki Ishizeki, Yasuaki Saijo, Tsuyoshi Yanagimachi, Manami Maeda, Ryoichi Bessho, Takao Takiyama, Hiroya Kitsunai, Hidemitsu Sakagami, Daisuke Fujishiro, Yukihiro Fujita, Yuichi Makino, Atsuko Abiko, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Tsuguhito Ota, Masakazu Haneda.
    EBioMedicine. 2018, 36C:401-425.
  34. A nonlinear dynamic finite element analyses of the basketball-related eye injuries.
    Alireza Karimi*, Reza Razaghi, Seyed Mohammadali Rahmati, Toshihiro Sera, Susumu Kudo.
    Sports. Eng. 2018, 21:359-365.
  35. A comparative study to determine the optimal intravitreal injection angle to the eye: A computational fluid-structure interaction model.
    Alireza Karimi*, Reza Razaghi, Hamideh Sabbaghi, Toshihiro Sera, Susumu Kudo.
    Technol. Health Care. 2018, 26:483-498.
  36. Spatial and temporal translocation of PKCα in single endothelial cell in response to mechanical stimulus.
    Masataka Arai, Toshihiro Sera, Takumi Hasegawa, Susumu Kudo*.
    Exp. Cell Res. 2018, 367:205-215.
  37. Collision of the glass shards with the eye: A computational fluid-structure interaction model.
    Alireza Karimi*, Reza Razaghi, Hasan Biglari, Toshihiro Sera, Susumu Kudo.
    J. Chem. Neuroanat. 2018, 90:80-86.
  38. Effect of shear stress on the migration of hepatic stellate cells.
    Toshihiro Sera*, Tateki Sumii, Ryosuke Fujita, Susumu Kudo.
    In Vitro Cell. Dev. Biol.-Anim. 2018, 54:11-22.
    39. 2017
  39. A combination of constitutive damage model and Artificial Neural Networks to characterize the mechanical properties of the healthy and atherosclerotic human coronary arteries.
    Alireza Karimi*, Seyed Mohammadali Rahmati, Toshihiro Sera, Susumu Kudo, Mahdi Navidbakhsh.
    Artf. Organs. 2017, 41:E103-E117.
  40. Biphasic and directed translocation of protein kinase Cα inside cultured endothelial cells before migration.
    Masataka Arai, Tomoya Shimada, Chihiro Kora, Kazuhiro Nakashima, Toshihiro Sera, Susumu Kudo*.
    Biochem. Biophys. Rep. 2017, 12:91-97.
  41. Strain measurements of the tibial insert of a knee prosthesis using a knee motion simulator.
    Toshihiro Sera*, Yuya Iwai, Takaharu Yamazaki, Tetsuya Tomita, Hideki Yoshikawa, Hisahi Naito, Takeshi Matsumoto, Masao Tanaka.
    J. Orthop. 2017, 14:495-500.
  42. Mechanical properties of the human sclera under various strain rates: Elastic, hyperelastic, and viscoelastic models.
    Alireza Karimi*, Reza Razaghi, Toshihiro Sera, Susumu Kudo.
    J. Biomater. Tissue Eng. 2017, 7:686-695.
  43. Distribution of nanoparticle depositions after a single breathing in a murine pulmonary acinus model.
    Toshihiro Sera*, Ryosuke Higashi, Hisashi Naito, Takeshi Matsumoto, Masao Tanaka.
    Int. J. Heat Mass Transfer. 2017, 108:730-739.
  44. Computing the influences of different intraocular pressures on the human eye components using computational fluid-structure interaction model.
    Alireza Karimi*, Reza Razaghi, Mahdi Navidbakhsh, Toshihiro Sera, Susumu Kudo.
    Technol. Health Care. 2017, 25:285-297.
    45. 2016
  45. Experimental verification of the healthy and atherosclerotic coronary arteries incompressibility via digital image correlation.
    Alireza Karimi*, Shahrokh Rahmani Toshihiro Sera, Susumu Kudo, Mahdi Navidbakhsh.
    Artery. Res. 2016, 16:1-7.
  46. Morphological characterization of acinar cluster in mouse lung using a multiscale-based segmentation algorithm on synchrotron micro-CT images.
    Luosha Xiao, Toshihiro Sera, Kenichiro Koshiyama, Shigeo Wada*.
    Anat. Rec. 2016, 299:1424-1434.
  47. A Combination of Experimental and Numerical Methods to Investigate the Role of Strain Rate on the Mechanical Properties and Collagen Fiber Orientations of the Healthy and Atherosclerotic Human Coronary Arteries.
    Alireza Karimi*, Seyed Mohammadali Rahmati, Toshihiro Sera, Susumu Kudo, Mahdi Navidbakhsh.
    Bioengineered. 2016, 8:154-170.
  48. Dynamic finite element simulation of the gunshot injury to the human forehead protected by polyvinyl alcohol sponge.
    Alireza Karimi*, Reza Razaghi, Mahdi Navidbakhsh, Toshihiro Sera, Susumu Kudo.
    J. Mater. Sci.-Mater. Med. 2016, 27:74.
  49. Computing the stresses and deformations of the human eye components due to a high explosive detonation using fluid-structure interaction model.
    Alireza Karimi*, Reza Razaghi, Toshihiro Sera, and Susumu Kudo.
    Injury. 2016, 47:1042-01050.
  50. Quantifying the injury of the human eye components due to tennis ball impact using a computational fluid-structure interaction model.
    Alireza Karimi*, Reza Razaghi, Mahdi Navidbakhsh, Toshihiro Sera, Susumu Kudo.
    Sports Eng. 2016, 19:105-115.
  51. The effect of nitric oxide on ammonia decomposition in co-cultures of hepatocytes and hepatic stellate cells.
    Tateki Sumii*, Yohei Nakano, Takuma Abe, Kazuhiro Nakashima, Toshihiro Sera, Susumu Kudo.
    In Vitro Cell. Dev. Biol.-Anim. 2016, 52:625-631.
  52. Measurement of the mechanical properties of soccer balls using digital image correlation method.
    Alireza Karimi*, Reza Razaghi, Mahdi Navidbakhsh, Toshihiro Sera, Susumu Kudo.
    Sport Sci. Health. 2016, 12:69-76.
  53. Effects of nitric oxide on ammonia decomposition by hepatocytes under shear stress, Journal of Biorheology.
    Tateki Sumii*, Yohei Nakano, Takuma Abe, Kazuhiro Nakashima, Toshihiro Sera, Susumu Kudo.
    J. Biorheol. 2016, 30:19-26.
    54. 2015
  54. Pulmonary kinematic analysis with non-rigid deformable registration for detecting localized emphysema.
    Ryosuke Higashi, Toshihiro Sera*, Hisashi Naito, Takeshi Matsumoto, Masao Tanaka.
    Comp. Meth. Biomech. Biomed. Eng. 2015, 5:100-109.
    55. 2014
  55. Numerical simulation of airflow and microparticle deposition in a synchrotron micro-CT based pulmonary acinus model.
    Toshihiro Sera*, Kentaro Uesugi, Naoto Yagi, and Hideo Yokota.
    Comput. Methods Biomech. Biomed. Eng. 2014, 18:1427-1435.
  56. Visualization of particle deposition in human nasal cavities.
    H. Sakai，Y. Watanabe，T. Sera，H. Yokota，G. Tanaka*.
    J. Vis. 2014, 18:349-357.
    57. 2013
  57. Influence of synovia constituents on tribological behaviors of articular cartilage.
    Teruo Murakami*, Seido Yarimitsu, Kazuhiro Nakashima, Yoshinori Sawae, Nobuo Sakai.
    Friction. 2013, 1:150-162.
  58. Gas dispersion of oscillatory flow in expanding and contracting multi-branching airways.
    Toshihiro Sera*, Hideo Yokota, Ryutaro Himeno, Gaku Tanaka.
    Int. J. Heat Mass Transfer. 2013, 65:627-634.
  59. X-ray micro-tomography using white beam radiation from SPring-8.
    Masato Hoshino*, Kentaro Uesugi, Toshihiro Sera, Naoto Yagi.
    J. Instrum. 2013, 8:P07018.
  60. Murine pulmonary acinar mechanics during quasi-static inflation using synchrotron refraction-enhanced CT.
    Toshihiro Sera*, Hideo Yokota, Gaku Tanaka, Kentaro Uesugi, Naoto Yagi, Robert C Schroter.
    J. Appl. Physiol. 2013, 115:218-223.
  61. Development of X-ray triscopic imaging system towards three-dimensional measurements of dynamical samples.
    Masato Hoshino*, Toshihiro Sera, Kentaro Uesugi, Naoto Yagi.
    J. Instrum. 2013, 8:C05002.
  62. A semi-automatic segmentation algorithm for extracting pulmonary microstructures of acini from synchrotron micro-CT images.
    Luosha Xiao, Toshihiro Sera, Kenichiro Koshiyama, Shigeo Wada*.
    Comput. Math. Method. Med. 2013, 2013:575086.
  63. Airway distension during lung inflation in healthy and allergic-sensitised mice in vivo.
    Toshihiro Sera*, Hideo Yokota, Kentaro Uesugi, Naoto Yagi.
    Respir. Physiol. Neuro. 2013, 185:639-546.
    64. 2012
  64. Effect of Flow Load on Hepatic Function in Co-Culture of Hepatocytes with Hepatic Stellate Cells and Endothelial Cells: Relationship between Hepatic Function and Nitric Oxide Concentration in vitro.
    Tateki SUMII*, Ryosuke FUJITA, Kazuo TANISHITA, Susumu KUDO.
    J. Biomech. Sci. Eng. 2012, 7:237-247.
  65. Albumin Permeability across Endothelial Monolayers under Pulsatile Shear Stress.
    Susumu Kudo, Minoru Kawarabayashi, Mariko Ikeda, Kazuo Tanishita.
    J. Biorheol. 2012, 26:38-43.
  66. Kinematic irreversibility of oscillatory flow in expanding and contracting small airways.
    Gaku Tanaka*, Masayoshi Ohgawara, Genri Inagaki, Makoto Hishida, Toshihiro Sera.
    Int. J. Heat Mass Transfer. 2012, 55:1873-1880.

Japanese articles & MISC